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Zebedin-Brandl, Eva-Maria


Hematopoietic stem and progenitor cells, exploratory nonclinical pharmacology, G protein coupled receptors, cell therapy, drug repurposing, translational pharmacology

Research Projects

2016: “Treprostinil for the prevention of veno-occlusive disease” (industrial funding, § 27 Project UG 2002)

2020: “Activation of Gαs coupled EP2 receptors” (industrial funding, § 27 Project UG 2002), BG-Covid-project MUW-APCOV40BGM (funded by the Medical-scientific Fund of the Mayor of Vienna)

Selected Publications

  1. Fiber type conversion alters inactivation of voltage-dependent sodium currents in murine C2C12 skeletal muscle cells. Zebedin E, Sandtner W, Galler S, Szendroedi J, Just H, Todt H, Hilber K. Am J Physiol Cell Physiol. 2004 Aug;287(2):C270-80. doi: 10.1152/ajpcell.00015.2004.
  2. C2C12 skeletal muscle cells adopt cardiac-like sodium current properties in a cardiac cell environment. Zebedin E, Mille M, Speiser M, Zarrabi T, Sandtner W, Latzenhofer B, Todt H, Hilber K. Am J Physiol Heart Circ Physiol. 2007 Jan;292(1):H439-50. doi: 10.1152/ajpheart.00119.2006.
  3. Effects of duramycin on cardiac voltage-gated ion channels. Zebedin E*, Koenig X*, Radenkovic M, Pankevych H, Todt H, Freissmuth M, Hilber K. Naunyn Schmiedebergs Arch Pharmacol. 2008 Mar;377(1):87-100. doi: 10.1007/s00210-007-0248-5. *equally contributed
  4. Leukemic challenge unmasks a requirement for PI3Kdelta in NK cell-mediated tumor surveillance. Zebedin E, Simma O, Schuster C, Putz EM, Fajmann S, Warsch W, Eckelhart E, Stoiber D, Weisz E, Schmid JA, Pickl WF, Baumgartner C, Valent P, Piekorz RP, Freissmuth M, Sexl V. Blood. 2008 Dec 1;112(12):4655-64. doi: 10.1182/blood-2008-02-139105.
  5. A novel Ncr1-Cre mouse reveals the essential role of STAT5 for NK-cell survival and development. Eckelhart E, Warsch W, Zebedin E, Simma O, Stoiber D, Kolbe T, Rülicke T, Mueller M, Casanova E, Sexl V. Blood. 2011 Feb 3;117(5):1565-73. doi: 10.1182/blood-2010-06-291633.

Assoc. Prof. Eva Maria Zebedin-Brandl, PhD