James D. Johnson, PhD
Associate Director, Vancouver Coastal Health Research Institute
Professor, UBC Faculty of Medicine
Vancouver, Canada
Programm
“Beta cell activity states and diabetes”
Abstract
Both type 1 diabetes and type 2 diabetes require the loss of pancreatic beta cell function. However, before the onset of diabetes there is evidence that beta cells can be hyperactive, potentially driving cell autonomous and non-cell autonomous pathological events. In this lecture, the role of beta cell hyperactivity will be discussed. We will discuss approaches reduce beta-cell activity that can prevent diabetes. The concept that beta cells can exist in high and low activity states will be highlighted using functional, transcriptomic, and proteomic profiling.
Biosketch
Dr. Jim Johnson, PhD, is a professor in the Department of Cellular and Physiological Sciences and the Department of Surgery at the University of British Columbia (UBC) and associate director at the Vancouver Coastal Health Research Institute. A world leader in the biology of pancreatic islets, insulin action, diabetes, and related conditions, Dr. Johnson has authored more than 120 peer-reviewed articles since 2000. He also co-founded the Institute for Personalized Therapeutic Nutrition in Vancouver in 2016 and served as the inaugural site head of the Novo Nordisk Research Centre in Oxford from 2016 to 2018. His interdisciplinary research spans fundamental cell physiology to clinical trials, aiming to elucidate the etiology of metabolic diseases.
Prof. Johnson is actively involved in science outreach on multiple social media sites @JimJohnsonSci.
Host: Marian SLAK-RUPNIK
Contact for questions: Helmut KUBISTA