Prof. Christoph WILHELM
University of Bonn
Clinical Chemisty and Clinical Pharmacology
Website Wilhelm-Lab
Programm
“Metabolic cooperations fueling barrier immunity”
The Wilhelm lab studies the metabolic control of mucosal immune cells. Specifically, the lab aims to determine how dietary restriction and fasting affect the immune system, and how exogenous and endogenous metabolites influence tissue-resident immune cells and barrier immunity. Recent work revealed that a ketogenic diet can be an effective dietary intervention strategy for treating chronic airway inflammation, and that ketogenesis triggered by severe respiratory infections supports T cell function by providing ketone bodies as an alternative carbon source. The lab's overarching goal is to understand the link between Westernization and the growing health problem of chronic inflammation, as well as the increased immune-mediated pathology in people with metabolic diseases.
Host:Gernot SCHABBAUER
Contact for questions: Helmut KUBISTA