Prof. Ferdinando FUIMARA
Università di Torino
Laboratory of Neurobiology and Molecular Genetics
Website Fiumara-Lab

Program

"Physiopathological roles of polyQ and other amino acid repeats in proteins"

Amino acid repeats are frequently found in proteins. Polyglutamine (polyQ) and other repeats have been initially studied in relation to neurodegenerative and developmental genetic disorders caused by their expansion, such as Huntington disease and cleidocranial dysplasia. However, a growing body of evidence indicates that these repetitive protein regions also have several important physiological roles. In this seminar, I will present our ongoing work on the evolution, structure, function, and pathological dysfunction of polyQ, and other amino acid repeats, in proteins.

Host: Francisco MONJE QUIROGA

Contact for questions: Helmut KUBISTA